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Production of ATP is controlled by a group of intracellular proteins called the "mitochondrial respiratory chain complex." These proteins (referred to as complexes I-IV ) control enzymatic reactions that convert energy substrates like oxygen, carbohydrates, and fatty acids into ATP by way of a metabolic pathway called oxidative phosphorylation

Glycine also participates in protein synthesis, in detoxification reactions, and has anti-inflammatory, cytoprotective and immunomodulatory properties

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SIRT1/PGC-1 signaling promotes mitochondrial functional recovery and reduces apoptosis after intracerebral hemorrhage in rats